Booth N A, Bennett B
Br J Haematol. 1982 Mar;50(3):537-41. doi: 10.1111/j.1365-2141.1982.tb01950.x.
alpha 2-Antiplasmin is the principal plasma inhibitor of plasmin, with which it rapidly and irreversibly forms a complex. The simple technique of crossed immunoelectrophoresis against antiserum to alpha 2-antiplasmin has been applied to detect plasmin-alpha 2-antiplasmin complex in plasma. The presence of this complex is demonstrated in patients in whom overactive fibrinolysis was the only or major contributor to severe haemorrhagic disorders arising spontaneously.
α2-抗纤溶酶是纤溶酶的主要血浆抑制剂，它能与之迅速且不可逆地形成复合物。针对α2-抗纤溶酶抗血清的交叉免疫电泳这一简单技术已被用于检测血浆中的纤溶酶-α2-抗纤溶酶复合物。在原发性严重出血性疾病中，若纤溶活性亢进是唯一或主要原因，则患者体内可检测到该复合物。
