Dawkins H J, Thomason H J, Grove D I
J Helminthol. 1982 Mar;56(1):45-50. doi: 10.1017/s0022149x00034994.
The migration of infective larvae of Strongyloides ratti has been examined in C57Bl/6 mice after percutaneous infection of the anterior abdominal wall. Lateral migration of larvae through the skin and subcutaneous tissues was not seen. Large numbers of larvae were recovered from the muscles between 2 and 24 hours after infection and larvae were seen in the cerebrospinal fluid 24 and 48 hours after infection. Insignificant numbers of larvae were seen in the blood, serosal cavities, liver, spleen, kidneys, brain or nasopharynx. Larvae arrived in the lungs between 24 and 72 hours after infection and worms were first noted in the small intestines at 48 hours. It is concluded that larvae migrate preferentially to the muscles and CSF before passing to the lungs, but the exact mode of travel is uncertain.
在经腹壁进行皮肤感染后，对C57Bl/6小鼠体内的鼠类圆线虫感染性幼虫的移行情况进行了研究。未观察到幼虫经皮肤和皮下组织的横向移行。感染后2至24小时，在肌肉中发现大量幼虫，感染后24和48小时，在脑脊液中发现幼虫。在血液、浆膜腔、肝脏、脾脏、肾脏、脑或鼻咽部发现的幼虫数量极少。感染后24至72小时，幼虫到达肺部，48小时时首次在小肠中发现成虫。得出的结论是，幼虫在进入肺部之前优先移行至肌肉和脑脊液，但确切的移行方式尚不确定。
