Gordon C R, Lavie P
Physiol Behav. 1984 Mar;32(3):345-50. doi: 10.1016/0031-9384(84)90246-4.
Different results are reported for the effects of an alpha and beta adrenergic blocker on the 24-hr sleep-wake patterns in dogs. While propranolol did not affect the 24-hr sleep-wake parameters, phentolamine significantly reduced delta sleep (stage 2), shortened the length of the sleep episodes, and decreased the number of REM episodes in each sleep-wake cycle. Phentolamine effects are explained by increased arousals within sleep episodes.
关于α和β肾上腺素能阻滞剂对犬24小时睡眠-觉醒模式的影响，已有不同的研究结果报道。虽然普萘洛尔不影响24小时睡眠-觉醒参数，但酚妥拉明显著减少了δ睡眠（第2阶段），缩短了睡眠时段的长度，并减少了每个睡眠-觉醒周期中的快速眼动睡眠时段数量。酚妥拉明的作用可通过睡眠时段内觉醒增加来解释。
