Guelinckx P J, Boeckx W D, Fossion E, Gruwez J A
Plast Reconstr Surg. 1984 Aug;74(2):217-26. doi: 10.1097/00006534-198408000-00008.
Irradiated and control recipient blood vessels in a similar patient population were studied with scanning electron microscopy. The vessels that were biopsied were then anastomosed to a free flap. Irradiated arteries display a significantly greater wall thickness and higher incidence of intimal dehiscence compared with control arteries. Fibrin deposition, microthrombi, and endothelium cell dehiscence are present more frequently in irradiated vessels than in control vessels. Details of the preparation and anastomotic technique for irradiated blood vessels are discussed. Microvascular surgery in irradiated human blood vessels carries with it a higher risk of thrombosis due to preexisting vessel wall damage. This risk can be minimized by experience and attention to detail.
在相似患者群体中，对接受过放疗的和对照受者的血管进行了扫描电子显微镜研究。然后将活检的血管与游离皮瓣进行吻合。与对照动脉相比，接受过放疗的动脉显示出明显更厚的管壁以及更高的内膜裂开发生率。与对照血管相比，接受过放疗的血管中更频繁地出现纤维蛋白沉积、微血栓和内皮细胞裂开。讨论了接受过放疗的血管的制备和吻合技术细节。由于先前存在的血管壁损伤，在接受过放疗的人体血管中进行微血管手术会带来更高的血栓形成风险。通过经验和对细节的关注，这种风险可以降至最低。
