Challamel M J, Isnard H, Brunon A M, Revol M
Rev Electroencephalogr Neurophysiol Clin. 1984 Jun;14(1):17-23. doi: 10.1016/s0370-4475(84)80029-5.
75 transient EEG asymmetries occurring during quiet sleep were studied. These asymmetries were obtained from 73 polygraphic recordings registered in 73 neonates. These infants represented 3.17% of all the neonates registered during the neonatal period in a department of neonatology (2297 neonates registered between July 1974 and July 1982). The pattern of these asymmetries was always identical, it consisted of a sudden flattening of the EEG activity occurring on one hemisphere followed on this hemisphere by an EEG activity which was more discontinuous and less mature than on the other hemisphere. These asymmetries were transient, lasting from 1 to 5 min. They occurred at the beginning of quiet sleep. The EEG activity before and after the asymmetry was almost always normal. The analysis of the clinical data showed that the infants who presented an EEG asymmetry during quiet sleep had a conceptional age ranging from 35 to 44 weeks, and that they were hospitalized for a minor illness which turned out to be a neurological disorder in only 2 cases. It showed that all the infants who were followed later, except one, developed normally. The physiological mechanism of these asymmetries is discussed and it is concluded that they are functional, probably enhanced by a sleep deprivation and not associated with a focal pathology.
对安静睡眠期间出现的75种短暂性脑电图不对称情况进行了研究。这些不对称情况取自73名新生儿的73份多导记录。这些婴儿占某新生儿科新生儿期登记的所有新生儿的3.17%（1974年7月至1982年7月期间登记了2297名新生儿）。这些不对称情况的模式总是相同的，表现为一个半球上的脑电图活动突然变平，随后该半球上的脑电图活动比另一个半球更不连续且更不成熟。这些不对称情况是短暂的，持续1至5分钟。它们出现在安静睡眠开始时。不对称前后的脑电图活动几乎总是正常的。临床数据分析表明，在安静睡眠期间出现脑电图不对称的婴儿胎龄为35至44周，他们因小病住院，其中只有2例后来被证明是神经疾病。结果显示，除1例婴儿外，所有随后接受跟踪观察的婴儿发育正常。文中讨论了这些不对称情况的生理机制，并得出结论，它们是功能性的，可能因睡眠剥夺而增强，且与局灶性病变无关。
