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[嗅球切除对大鼠血浆葡萄糖、脂质和皮质酮水平的影响]

[Effect of olfactory bulbectomy on plasma levels of glucose, lipids and corticosterone in the rat].

作者信息

Montilla P, Varo A, Muñoz M C

出版信息

Rev Esp Fisiol. 1984 Mar;40(1):47-51.

PMID:6463342
Abstract

The effect of bilateral olfactory bulbs removal on the peripheral glucose, lipids and corticosterone levels has been studied in Wistar male rats. After 30 days of the olfactory bulbectomy there was found: an increase in the basal values of plasmatic glucose, a significant increase in peripheral levels of the free fatty acids, and a notorius decrease in plasmatic corticosterone at 9 a.m. Other biochemical parameters, such as free glycerol, triglycerides and phospholipids, went unaltered. These after bulbectomy variations, especially the increase in free fatty acids, are discussed in relation to a possible role of the olfactory bulbs on the nutritional, endocrine and nervous factors, which are closely related to the mechanisms involved in the regulation of cellular lypolisis.

摘要

在雄性Wistar大鼠中研究了双侧嗅球切除对外周葡萄糖、脂质和皮质酮水平的影响。嗅球切除30天后发现:血浆葡萄糖基础值升高,游离脂肪酸外周水平显著升高,上午9点时血浆皮质酮显著降低。其他生化参数,如游离甘油、甘油三酯和磷脂,未发生变化。本文讨论了嗅球切除术后的这些变化,特别是游离脂肪酸的增加,与嗅球在营养、内分泌和神经因素方面可能发挥的作用有关,这些因素与细胞脂肪分解调节机制密切相关。

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Rev Esp Fisiol. 1984 Mar;40(1):47-51.
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