Stark W J, Maumenee A E, Fagadau W, Datiles M, Baker C C, Worthen D, Klein P, Auer C
Surv Ophthalmol. 1984 May;28 Suppl:442-51. doi: 10.1016/0039-6257(84)90226-1.
Cystoid macular edema after cataract surgery, with or without intraocular lens implantation, has been reported to develop in more than 50% of patients as detected by fluorescein angiography. It is associated with reduced visual acuity in up to 8% of cases. Analysis of ongoing clinical trials at the Wilmer Institute indicates that clinically significant cystoid macular edema develops in a lower percentage of cases (2% total incidence and 0.3% persistent cystoid macular edema) if the intraocular lens implantation was uncomplicated. The factors associated with cystoid macular edema and the importance of considering clinically significant rather than just fluorescein-proven cystoid macular edema are discussed. Results of intraocular lens studies reported to the Federal Drug Administration are updated, and results of an ongoing study of prostaglandin inhibitors at the Wilmer Institute are reported.
据报道，白内障手术后无论是否植入人工晶状体，经荧光素血管造影检测，超过50%的患者会发生囊样黄斑水肿。在高达8%的病例中，它与视力下降有关。威尔默眼科研究所正在进行的临床试验分析表明，如果人工晶状体植入过程未出现并发症，临床上显著的囊样黄斑水肿发生率较低（总发生率为2%，持续性囊样黄斑水肿为0.3%）。本文讨论了与囊样黄斑水肿相关的因素，以及考虑临床上显著的而非仅经荧光素证实的囊样黄斑水肿的重要性。更新了向美国食品药品监督管理局报告的人工晶状体研究结果，并报告了威尔默眼科研究所正在进行的前列腺素抑制剂研究结果。
