地中海贫血患者的血清25-羟基维生素D水平
Serum 25-hydroxyvitamin D levels in thalassaemia.
作者信息
Tsitoura S, Amarilio N, Lapatsanis P, Pantelakis S, Doxiadis S
出版信息
Arch Dis Child. 1978 Apr;53(4):347-8. doi: 10.1136/adc.53.4.347.
Abstract
Serum 25-hydroxyvitamin D levels were measured in 36 thalassaemic children and 27 controls aged 5-15 years. Blood specimens were collected from the beginning of April until the end of October 1976. We considered as the winter period the first 3 months and the summer period the last 4 months. We found that (a) thalassaemic children had lower levels of serum 25-hydroxyvitamin D than controls: (b) there was a seasonal variation of serum 25-hydroxyvitamin D in both groups; and (c) the thalassaemic children had malabsorption of vitamin D. We suggest that the bone lesions in thalassaemic children are related to vitamin D deficiency.
摘要
对36名5至15岁的地中海贫血儿童和27名对照儿童测定了血清25-羟基维生素D水平。血液样本采集于1976年4月初至10月底。我们将前3个月视为冬季，后4个月视为夏季。我们发现：（a）地中海贫血儿童的血清25-羟基维生素D水平低于对照组；（b）两组的血清25-羟基维生素D均有季节性变化；（c）地中海贫血儿童存在维生素D吸收不良。我们认为地中海贫血儿童的骨病变与维生素D缺乏有关。
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