Dupuis M, Brucher J M, Gonsette R E
Acta Neurol Belg. 1984 May-Jul;84(3):131-40.
A 54 year-old hypertensive female patient presented dementia evolving progressively over a four-year period in association with motor deficiency and asymmetric pyramidal signs. The scan showed diffuse hypodensity of the white matter without enhancement. Brain biopsy indicated a diagnosis of subcortical arteriosclerotic encephalopathy; this was later confirmed by the post-mortem examination. On the strength of data from the literature, the authors draw attention to the frequency of this syndrome in hypertensive patients. They outline the main clinical characteristics and demonstrate the importance of the scan.
一名54岁的高血压女性患者在四年时间里逐渐出现痴呆症状,并伴有运动功能障碍和不对称锥体束征。扫描显示白质弥漫性低密度,无强化。脑活检诊断为皮质下动脉硬化性脑病;尸检后来证实了这一诊断。基于文献数据,作者提请注意该综合征在高血压患者中的发生率。他们概述了主要临床特征,并证明了扫描的重要性。