Lawrence D, Fish P J, Kakkar V V
Lancet. 1977 Jan 15;1(8003):117-8. doi: 10.1016/s0140-6736(77)91705-6.
A new pulsed multichannel ultrasonic Doppler instrument was used to determine the relative blood-flow in the perforating veins of 16 patients with symptoms attributable to their leg venous systems. 9 patients had leg ulceration and 7 did not. 8 (89%) of the ulcer patients had sustained blood-flow from the deep to the superficial veins ("reverse") during calf muscle contraction, compared to 1 (14%) of the group without leg ulcers. This evidence supports the theory that postphlebitic leg ulceration is the result of retrograde flow of blood in incompetent calf perforating veins during walking.
一种新型脉冲多通道超声多普勒仪被用于测定16例有腿部静脉系统相关症状患者的穿通静脉相对血流量。9例患者有腿部溃疡,7例没有。在小腿肌肉收缩时,8例(89%)溃疡患者存在从深静脉到浅静脉的持续血流(“逆流”),相比之下,无腿部溃疡组中这一比例为1例(14%)。这一证据支持了如下理论:静脉炎后腿部溃疡是行走时小腿穿通静脉功能不全导致血液逆流的结果。