Pudney J, Callard G V
Anat Rec. 1984 Jul;209(3):323-30. doi: 10.1002/ar.1092090310.
The site of hormone synthesis in the testis of elasmobranchs has been the subject of much controversy. This is primarily due to the problem of whether Leydig cells are present or absent in the testes of many species of elasmobranchs. In previous studies we have shown that key enzymes associated with the biosynthesis of androgen increase in activity during the spermatogenetic cycle of Squalus acanthias (Canick et al., 1983). To determine the site of this activity we undertook an electron microscope study of Squalus testes to identify cells that possessed the structural correlates of steroid production. This report describes cells present in the interstitial tissue that are morphologically analogous to Leydig cells occurring in the testes of higher vertebrates. Although these cells possessed an agranular reticulum, tubulovesicular mitochondria, and lipid droplets, they were mesenchymal in appearance. We have, therefore, preferred to describe these cells as Leydig-like.
软骨鱼类睾丸中激素合成的部位一直是众多争议的焦点。这主要是由于许多软骨鱼类的睾丸中是否存在莱迪希细胞这一问题。在之前的研究中，我们已经表明，与雄激素生物合成相关的关键酶在棘鲨精子发生周期中活性增加（卡尼克等人，1983年）。为了确定这种活性的部位，我们对棘鲨睾丸进行了电子显微镜研究，以识别具有类固醇产生结构特征的细胞。本报告描述了间质组织中存在的细胞，这些细胞在形态上类似于高等脊椎动物睾丸中的莱迪希细胞。尽管这些细胞具有无颗粒内质网、管状泡状线粒体和脂滴，但它们外观呈间充质样。因此，我们更倾向于将这些细胞描述为类莱迪希细胞。
