Laurent P, Charles J F
Ann Microbiol (Paris). 1984 May-Jun;135A(3):473-84.
Crystals isolated from Bacillus thuringiensis serovar thuringiensis (H-1) and from serovar israelensis (H-14) were dissolved in sodium hydroxide, then tested in vitro on Aedes aegypti cell cultures. Toxic action was followed after morphological and metabolic alterations of the treated cells. Only the israelensis sodium extract was toxic and gave cellular swelling, inhibition of cell growth and inhibition of labelled precursor incorporation, i. e. of 3H-thymidine, 3H-uridine and 3H-leucine.
从苏云金芽孢杆菌苏云金亚种（H-1）和以色列亚种（H-14）中分离出的晶体溶解于氢氧化钠中，然后在埃及伊蚊细胞培养物上进行体外测试。在处理过的细胞发生形态和代谢改变后，观察其毒性作用。只有以色列亚种的钠提取物具有毒性，可导致细胞肿胀、细胞生长抑制以及标记前体掺入的抑制，即对³H-胸腺嘧啶核苷、³H-尿苷和³H-亮氨酸的掺入抑制。
