Dreyer R F, Hopen G, Gass J D, Smith J L
Arch Ophthalmol. 1984 Aug;102(8):1140-5. doi: 10.1001/archopht.1984.01040030918013.
Twenty-nine eyes of 27 patients demonstrated the typical features of neuroretinitis with a mascular star. Historical and fluorescein angiographic features of this condition implicate a bloodborne infectious agent. It is likely that multiple agents can produce this condition, including the agent of cat-scratch fever and leptospirosis. A small subgroup may exist in whom this condition resembles anterior ischemic optic neuropathy and has a less favorable clinical course than is usual. There is evidence that this condition is not related to demyelinating disease. It is emphasized that this condition is not a maculopathy since vascular leakage in the optic nerve causes the star. Therefore, we suggest that this condition be renamed Leber's idiopathic stellate neuroretinitis.
27例患者的29只眼睛表现出伴有黄斑星芒状渗出的典型视盘血管炎特征。该疾病的病史及荧光素血管造影特征提示存在血源性感染病原体。很可能多种病原体均可引发此疾病，包括猫抓热病原体及钩端螺旋体。可能存在一小部分患者，其病情类似前部缺血性视神经病变，临床病程较通常情况更为不利。有证据表明该疾病与脱髓鞘疾病无关。需要强调的是，由于视神经的血管渗漏导致了星芒状渗出，因此该病并非黄斑病变。所以，我们建议将此疾病重新命名为Leber特发性星芒状视盘血管炎。
