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2,3-二磷酸甘油酸抑制磷酸烯醇丙酮酸跨红细胞膜的转运。

2,3-Bisphosphoglycerate inhibits the transport of phosphoenolpyruvate across the erythrocyte membrane.

作者信息

Hamasaki N

出版信息

Biochem Biophys Res Commun. 1984 Jul 31;122(2):609-12. doi: 10.1016/s0006-291x(84)80076-5.

DOI:10.1016/s0006-291x(84)80076-5
PMID:6466329
Abstract

Mono- and bisphosphoglycerate competitively inhibited the transport of phosphoenolpyruvate across the erythrocyte membrane, although phosphoglycerates were impermeable to the cell membrane. The Ki values of 2-phosphoglycerate, 3-phosphoglycerate and 2,3-bisphosphoglycerate were 8.8 mM, 10.4 mM and 4.3 mM, respectively, whereas glucose 6-phosphate had almost no effect on the transport of phosphoenolpyruvate.

摘要

单磷酸甘油酸和二磷酸甘油酸竞争性抑制磷酸烯醇丙酮酸跨红细胞膜的转运，尽管甘油酸酯不能透过细胞膜。2-磷酸甘油酸、3-磷酸甘油酸和2,3-二磷酸甘油酸的Ki值分别为8.8 mM、10.4 mM和4.3 mM，而6-磷酸葡萄糖对磷酸烯醇丙酮酸的转运几乎没有影响。

相似文献

1
2,3-Bisphosphoglycerate inhibits the transport of phosphoenolpyruvate across the erythrocyte membrane.2,3-二磷酸甘油酸抑制磷酸烯醇丙酮酸跨红细胞膜的转运。
Biochem Biophys Res Commun. 1984 Jul 31;122(2):609-12. doi: 10.1016/s0006-291x(84)80076-5.
2
Regeneration of 2,3-bisphosphoglycerate and ATP in stored erythrocytes by phosphoenolpyruvate: a new preservative for blood storage.
Transfusion. 1981 Jul-Aug;21(4):391-6. doi: 10.1046/j.1537-2995.1981.21481275994.x.
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Effects of inorganic and organic anions on the transport of phosphoenol-pyruvate across the erythrocyte membrane.无机和有机阴离子对磷酸烯醇丙酮酸跨红细胞膜转运的影响。
Tokai J Exp Clin Med. 1982;7 Suppl:113-9.
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Characterization of phosphoenolpyruvate transport across the erythrocyte membrane. Evidence for involvement of band 3 in the transport system.磷酸烯醇丙酮酸跨红细胞膜转运的特性。关于带3参与转运系统的证据。
Eur J Biochem. 1983 May 16;132(3):531-6. doi: 10.1111/j.1432-1033.1983.tb07394.x.
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Rejuvenation of aged erythrocytes by incorporating phosphoenolpyruvate into the cells.通过将磷酸烯醇丙酮酸掺入细胞中来使衰老红细胞恢复活力。
Acta Biol Med Ger. 1981;40(4-5):691-7.
6
A 31P NMR study of phosphoenolpyruvate transport across the human erythrocyte membrane.
Biochem Biophys Res Commun. 1981 May 29;100(2):879-87. doi: 10.1016/s0006-291x(81)80255-0.
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The active center of transport for phosphoenolpyruvate and inorganic phosphate in the human erythrocyte membrane.人红细胞膜中磷酸烯醇丙酮酸和无机磷酸的主动运输中心。
Biomed Biochim Acta. 1987;46(2-3):S51-4.
8
Transport of phosphoenolpyruvate through the erythrocyte membrane.磷酸烯醇丙酮酸通过红细胞膜的转运。
Biochem J. 1978 Jan 15;170(1):39-46. doi: 10.1042/bj1700039.
9
[Red cell glycolytic intermediates].
Nihon Rinsho. 1995 Mar;53 Su Pt 2:234-8.
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Metabolism of 3-phosphoglyceroyl phosphate in phosphoenolpyruvate-enriched human erythrocytes.
J Biol Chem. 1987 Jun 5;262(16):7635-8.

引用本文的文献

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Characterization of 4,4'-Diisothiocyano-2,2'-disulfonic Acid Stilbene Inhibition of 3-Phosphoglycerate-Dependent O(2) Evolution in Isolated Chloroplasts : Evidence for a Common Binding Site on the C(4) Phosphate Translocator for 3-Phosphoglycerate, Phosphoenolpyruvate, and Inorganic Phosphate.4,4'-二异硫氰酸-2,2'-二磺酸芪对离体叶绿体中3-磷酸甘油酸依赖性O₂释放的抑制作用表征：关于C₄磷酸转运体上3-磷酸甘油酸、磷酸烯醇丙酮酸和无机磷酸共同结合位点的证据
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