Biagi P L, Maranesi M
Boll Soc Ital Biol Sper. 1984 May 30;60(5):1029-35.
Dietary fatty acid fraction influence on heart composition is known and we have previously demonstrated a trans-fatty acid accumulation in heart. In this work we will verify trans-fatty acid effect on heart phospholipid fatty acid composition and miocardic mitochondrial respiratory activity under the influence of perfusion techniques in oxygenation and anoxic conditions. Results have pointed out, in group fed with 28% trans-fatty acid hydrogenated fat, a decreased mitochondrial functionality during perfusion in different oxygenation condition, probably correlated to different fatty acid composition of heart phospholipids.
膳食脂肪酸组分对心脏组成的影响是已知的，并且我们之前已经证明了反式脂肪酸在心脏中的积累。在这项工作中，我们将在氧合和缺氧条件下的灌注技术影响下，验证反式脂肪酸对心脏磷脂脂肪酸组成和心肌线粒体呼吸活性的影响。结果指出，在喂食28%反式脂肪酸氢化脂肪的组中，在不同氧合条件下灌注期间线粒体功能降低，这可能与心脏磷脂的不同脂肪酸组成有关。
