Wyse R K, Robinson P J, Deanfield J E, Tunstall Pedoe D S, Macartney F J
Br Heart J. 1984 Sep;52(3):278-83. doi: 10.1136/hrt.52.3.278.
Peak ascending and descending aortic blood flow velocities were measured using continuous wave Doppler ultrasound velocimetry in 30 children with coarctation or recoarctation of the aorta and in 13 control subjects. The results were compared with the arm to leg systolic blood pressure difference. The peak flow velocities in the descending aorta were significantly higher in the patients than in the control subjects and there was a close correlation with the systolic blood pressure gradient. Since there was no overlap of flow velocities between the patients and the control subjects the Doppler technique enables coarctation confidently to be excluded as well as demonstrating its presence and severity. The method is simple, rapid, independent of the condition of the aortic valve, and is applicable to neonates in whom the diagnosis of coarctation may otherwise be difficult. In older children it is useful for detecting recoarctation and following its progress, particularly in patients in whom a reliable estimate of the systolic blood pressure gradient cannot be obtained.
采用连续波多普勒超声测速法，对30例患有主动脉缩窄或再缩窄的儿童以及13名对照受试者测量其升主动脉和降主动脉血流速度峰值。将结果与臂-腿收缩压差进行比较。患者降主动脉的血流速度峰值显著高于对照受试者，且与收缩压梯度密切相关。由于患者和对照受试者的血流速度没有重叠，多普勒技术能够可靠地排除主动脉缩窄，同时也能显示其存在及严重程度。该方法简单、快速，不受主动脉瓣状况的影响，适用于难以诊断主动脉缩窄的新生儿。对于年龄较大的儿童，该方法有助于检测再缩窄并跟踪其进展，尤其是对于无法可靠估计收缩压梯度的患者。
