Hatle L, Angelsen B A, Tromsdal A
Br Heart J. 1980 Mar;43(3):284-92. doi: 10.1136/hrt.43.3.284.
The peak pressure drop across the aortic valve in aortic stenosis has been measured by Doppler ultrasound. Maximum velocity in the Doppler signal from the aortic jet was recorded using a maximum frequency estimator. With an angle close to zero between ultrasound beam and maximal velocity in the jet, peak pressure drop can be calculated from the maximal velocity measured; a larger angle will underestimate maximal velocity and pressure drop. In 57 of 63 patients with aortic stenosis, the aortic jet could be reached by the ultrasound beam and, in 37 of these, peak pressure drop by ultrasound was compared with that obtained at catheterisation. In patients less than 50 years of age the aortic jet was easy to find, the measurement was reproducible, and underestimation of the pressure drop obtained at catheterisation was within 25 per cent in 17 of 18 patients. In patients over 50 years Doppler signals from the aortic jet were more difficult to obtain, and pressure drop was significantly underestimated in one-third, but time of maximum velocity in systole could indicate whether moderate or severe aortic stenosis was present.
通过多普勒超声测量了主动脉瓣狭窄时主动脉瓣两端的峰值压力差。使用最大频率估计器记录来自主动脉射流的多普勒信号中的最大速度。当超声束与射流中的最大速度之间的夹角接近零时，可根据测得的最大速度计算峰值压力差；夹角较大时会低估最大速度和压力差。在63例主动脉瓣狭窄患者中，有57例的超声束能够探测到主动脉射流，其中37例患者将超声测量的峰值压力差与心导管检查时测得的结果进行了比较。在年龄小于50岁的患者中，主动脉射流很容易找到，测量结果具有可重复性，18例患者中有17例超声测得的压力差低估幅度在25%以内。在年龄超过50岁的患者中，更难获取来自主动脉射流的多普勒信号，三分之一的患者压力差被显著低估，但收缩期最大速度的时间可提示是否存在中度或重度主动脉瓣狭窄。
