Borisenko S N, Troitskiĭ G V
Biull Eksp Biol Med. 1984 Jul;98(7):61-3.
A modified form of albumin isolated from the blood of oncological patients was studied. A modification of N-terminal amino acid, 50% tyrosine groups, free SH-group of cysteine and lysine group in the fourth position in the N-terminal sequence of amino acids was discovered. The possibility of a post-translation modification of serum albumin in disease in individual amino acid groups is discussed.
对从肿瘤患者血液中分离出的一种改良形式的白蛋白进行了研究。发现了N端氨基酸、50%的酪氨酸基团、半胱氨酸的游离巯基以及N端氨基酸序列中第四个位置的赖氨酸基团的修饰。讨论了疾病中血清白蛋白个别氨基酸基团发生翻译后修饰的可能性。