Wideman R F
Comp Biochem Physiol B. 1984;78(2):315-9. doi: 10.1016/0305-0491(84)90036-1.
Parathyroid hormone (PTH) stimulates net renal inorganic phosphate (Pi) secretion in domestic fowl (Gallus domesticus). Recent evidence indicates that secreted Pi is derived from a highly sequestered, presumably organic, phosphate pool. A modified Sperber technique was used to survey the response of domestic fowl to unilateral renal portal infusions of organic phosphate compounds that had been implicated in previous studies of Pi secretion. None of the organic phosphate compounds produced a significant unilateral Pi secretory effect. It is concluded that these compounds neither directly stimulate Pi secretion in normal or parathyroidectomized birds, nor are they rate-limiting for the Pi secretory mechanism in birds infused with PTH.
甲状旁腺激素(PTH)可刺激家鸡(原鸡)的肾脏净无机磷酸盐(Pi)分泌。最近的证据表明,分泌的Pi来源于一个高度隔离的、可能是有机的磷酸盐池。采用改良的斯珀伯技术,研究家鸡对单侧肾门静脉注入有机磷酸盐化合物的反应,这些化合物在先前的Pi分泌研究中曾被涉及。没有一种有机磷酸盐化合物产生显著的单侧Pi分泌效应。得出的结论是,这些化合物既不直接刺激正常或甲状旁腺切除的鸟类的Pi分泌,也不是注入PTH的鸟类Pi分泌机制的限速因素。