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中枢5-羟色胺耗竭对肾上腺皮质对神经刺激反应的影响。

Effect of central serotonin depletion on adrenocortical responses to neural stimuli.

作者信息

Feldman S, Melamed E, Conforti N, Weidenfeld J

出版信息

Exp Neurol. 1984 Sep;85(3):661-6. doi: 10.1016/0014-4886(84)90038-4.

DOI:10.1016/0014-4886(84)90038-4
PMID:6468582
Abstract

In view of the possible role of serotonin in adrenocortical regulation, basal plasma corticosterone concentrations and the response to ether stress, photic, acoustic, or sciatic nerve stimulation, were studied in rats with 5,7-dihydroxytryptamine or vehicle injected into the raphe nuclei. The neurotoxin inhibited the response to photic stimulation without affecting the other modalities. This may suggest that the depletion of brain serotonin has a differential effect on the transmission of neural impulses which activate the adrenal cortex.

摘要

鉴于血清素在肾上腺皮质调节中可能发挥的作用,我们对向中缝核注射5,7 - 二羟基色胺或赋形剂的大鼠,研究了其基础血浆皮质酮浓度以及对乙醚应激、光、声或坐骨神经刺激的反应。这种神经毒素抑制了对光刺激的反应,而不影响其他刺激方式。这可能表明,脑血清素的耗竭对激活肾上腺皮质的神经冲动传递具有不同的影响。

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Effect of central serotonin depletion on adrenocortical responses to neural stimuli.中枢5-羟色胺耗竭对肾上腺皮质对神经刺激反应的影响。
Exp Neurol. 1984 Sep;85(3):661-6. doi: 10.1016/0014-4886(84)90038-4.
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引用本文的文献

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Paraventricular nucleus neuronal responses following electrical stimulation of the midbrain dorsal raphe: evidence for cotransmission.中脑背侧缝际核电刺激后室旁核神经元反应:共传递的证据
Exp Brain Res. 1989;78(2):407-14. doi: 10.1007/BF00228913.
2
Differential recovery of adrenocortical responses to neural stimuli following administration of 5,7-dihydroxytryptamine into the hypothalamus.在下丘脑注射5,7-二羟基色胺后,肾上腺皮质对神经刺激反应的差异恢复。
Exp Brain Res. 1991;85(1):144-8. doi: 10.1007/BF00229995.