正常及去神经支配骨骼肌中的丙氨酸氨基转移酶和天冬氨酸氨基转移酶
Alanine and aspartate aminotransferases in normal and denervated skeletal muscle.
作者信息
Asotra K, Asotra S
出版信息
Experientia. 1984 Sep 15;40(9):951-3. doi: 10.1007/BF01946454.
PMID:6468620
Abstract
Activities of alanine and aspartate aminotransferases are maintained during the first 5 weeks of growth, but decrease subsequently in normal chick gastrocnemii. In sciatectomized muscles, a 5-fold elevation in these enzymes reveals increased utilization of amino acids as a compensatory metabolic support during denervation atrophy.
摘要
丙氨酸氨基转移酶和天冬氨酸氨基转移酶的活性在生长的前5周保持稳定，但随后在正常雏鸡的腓肠肌中下降。在坐骨神经切除的肌肉中，这些酶升高了5倍，这表明在去神经萎缩过程中，作为一种代偿性代谢支持，氨基酸的利用增加。
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