Houghton A, Hickey J B, Ross S A, Dupre J
Br J Anaesth. 1978 May;50(5):495-9. doi: 10.1093/bja/50.5.495.
The effects of general and extradural anaesthesia on glucose tolerance and plasma cortisol concentration in the surgical patient were assessed. Normal glucose tolerance and insulin release were observed under extradural anaesthesia, whereas general anaesthesia produced decreases in both glucose tolerance and insulin release. The plasma cortisol concentration was increased in both groups. These results indicate possible nutritional advantages in conducting surgery under extradural anaesthesia.
评估了全身麻醉和硬膜外麻醉对外科手术患者葡萄糖耐量及血浆皮质醇浓度的影响。硬膜外麻醉下观察到葡萄糖耐量和胰岛素释放正常,而全身麻醉则使葡萄糖耐量和胰岛素释放均降低。两组患者的血浆皮质醇浓度均升高。这些结果表明硬膜外麻醉下进行手术可能具有营养方面的优势。