Williams S J, Green M, Nicholls A
Br J Dis Chest. 1978 Apr;72(2):138-42. doi: 10.1016/0007-0971(78)90024-4.
The tuberculosis agglutination titre as described by Nicholls (1975) was measured without prior knowledge of the diagnosis in 27 patients with open pulmonary tuberculosis, 100 patients with other diseases and 14 control patients with no apparent disease. Reproducibility of the test, as judged by repeat estimations on split samples, was poor. When attempting to distinguish between the disease categories the test gave 29% false negatives in patients with tuberculosis and 52% false positives in patients with other disease. Therefore the tuberculosis agglutination titre cannot be recommended for use in distinguishing tuberculosis from other conditions.
按照尼科尔斯（1975年）所述方法，在对诊断不知情的情况下，测定了27例开放性肺结核患者、100例患有其他疾病的患者以及14例无明显疾病的对照患者的结核凝集滴度。根据对分离样本的重复测定判断，该检测的可重复性较差。在试图区分疾病类别时，该检测在肺结核患者中产生了29%的假阴性，在患有其他疾病的患者中产生了52%的假阳性。因此，不建议使用结核凝集滴度来区分结核病与其他病症。
