DiSalvo A F, Corbett D S
J Clin Microbiol. 1976 Mar;3(3):306-8. doi: 10.1128/jcm.3.3.306-308.1976.
Serum specimens from patients admitted to a respiratory disease hospital were examined by the histoplasmin latex agglutination, the complement fixation, and the agar gel immunodiffusion tests. Of 300 sera examined, 21 (7.0%) gave an apparent false positive reaction at a dilution of 1:16 or greater. Fourteen (66%) of the 21 patients studied has culturally proven tuberculosis. One patient each had a diagnosis of hypertensive cardiovascular disease with congestive heart failure, infection with atypical mycobacteria (Runyon group III), chronic pneumonitis secondary to gunshot wound, and pulmonary abscess of unknown etiology; two had bronchogenic carcinoma; and one serum specimen came from an apparently healthy employee. The results of the histoplasmin latex agglutination test should be interpreted with caution, particularly if only one serological determination has been made and the titer is low.
对一家呼吸道疾病医院收治患者的血清标本进行了组织胞浆菌素乳胶凝集试验、补体结合试验和琼脂凝胶免疫扩散试验。在检测的300份血清中，21份（7.0%）在1:16或更高稀释度时出现明显假阳性反应。在研究的21例患者中，14例（66%）经培养证实患有结核病。1例诊断为高血压性心血管疾病伴充血性心力衰竭，1例感染非典型分枝杆菌（Runyon III组），1例因枪伤继发慢性肺炎，1例病因不明的肺脓肿；2例患有支气管源性癌；1份血清标本来自一名看似健康的员工。组织胞浆菌素乳胶凝集试验结果的解释应谨慎，特别是如果仅进行了一次血清学检测且滴度较低时。
