Ling W, Wesson D R
J Clin Psychiatry. 1984 Sep;45(9 Pt 2):46-8.
Sixty physicians and other health-care professionals with narcotic dependency were treated with naltrexone, 300 to 350 mg/week, in private physicians' offices. Patients remained on naltrexone treatment for an average of 8 months. On a global scale rating the degree of improvement in drug abuse, professional activities, and psychosocial adjustment, 29 patients were rated much improved and 31 either moderately or slightly improved. When these two groups were compared, it was found that more patients in the much improved group did not drink (p less than .01) and remained in naltrexone treatment longer than 6 months (p less than .01). Patients in the much improved group were also older (p less than .01). Naltrexone, used in the private practice setting, appears to be a useful treatment adjunct for addicted health-care professionals.
60名有麻醉品依赖问题的医生和其他医疗保健专业人员在私人医生诊所接受了纳曲酮治疗，剂量为每周300至350毫克。患者接受纳曲酮治疗的平均时间为8个月。在对药物滥用、专业活动和心理社会适应方面的改善程度进行总体评分时，29名患者被评为改善显著，31名患者被评为中度或轻度改善。比较这两组时发现，改善显著组中更多患者不饮酒（p小于0.01），且接受纳曲酮治疗的时间超过6个月（p小于0.01）。改善显著组的患者年龄也更大（p小于0.01）。在私人执业环境中使用的纳曲酮似乎是治疗成瘾医疗保健专业人员的一种有用辅助药物。
