Kaplan W E, Firlit C F
J Urol. 1983 Jun;129(6):1195-7. doi: 10.1016/s0022-5347(17)52637-3.
More than 75 per cent of the patients with spinal dysrhaphisms followed at our hospital are on intermittent catheterization. A previous report indicated that 62 per cent of 200 children with reflux and a neurogenic bladder either ceased to have reflux or reflux was downgraded while on intermittent catheterization and chronic antibiotics. We report on those children in whom either reflux did not stop while on the program, or who presented with high grades of reflux not amenable to cure by intermittent catheterization. During the last 4 years 25 children (40 ureters) required antireflux surgery. The criterion of repair was persistent reflux of at least grade IIB, associated with recurrent episodes of infection. A modified Leadbetter-Politano technique was used in 5 children (7 ureters) and the Cohen cross-trigonal technique was used in 20 children (33 ureters). A successful result, that is cessation of reflux and no obstruction, was achieved in 96 per cent of the patients. During the last 2 years the Cohen cross-trigonal technique has been used exclusively and there have been no failures. This successful result in 96 per cent of the children with neurogenic bladder indicates that while clean intermittent catheterization should be used primarily to relieve reflux, in a select group of children antireflux surgery should be done and clean intermittent catheterization should be continued.
在我院接受随访的脊髓发育异常患者中,超过75%的患者采用间歇性导尿。先前的一份报告指出,200例患有反流和神经源性膀胱的儿童中,62%在进行间歇性导尿和长期使用抗生素治疗期间,反流停止或反流程度减轻。我们报告的是那些在该治疗方案下反流未停止,或存在难以通过间歇性导尿治愈的高度反流的儿童。在过去4年中,25名儿童(40条输尿管)需要进行抗反流手术。手术修复的标准是至少IIB级的持续性反流,并伴有反复感染发作。5名儿童(7条输尿管)采用改良的Leadbetter - Politano技术,20名儿童(33条输尿管)采用科恩三角交叉技术。96%的患者取得了成功的结果,即反流停止且无梗阻。在过去2年中,仅使用了科恩三角交叉技术,且无一例失败。96%的神经源性膀胱儿童取得的这一成功结果表明,虽然清洁间歇性导尿应主要用于缓解反流,但在一部分特定儿童中应进行抗反流手术,并继续进行清洁间歇性导尿。