Omoto R, Yokote Y, Takamoto S, Kyo S, Ueda K, Asano H, Namekawa K, Kasai C, Kondo Y, Koyano A
Jpn Heart J. 1984 May;25(3):325-40. doi: 10.1536/ihj.25.325.
A noninvasive method for real time blood-flow imaging using ultrasound has long been required in the fields of cardiology and cardiovascular surgery. Recently, we developed a method of two-dimensional Doppler echocardiography (hereafter abbreviated as "2-D Doppler") for clinical use which allows us to obtain noninvasively, intracardiac blood-flow images in real time. The main purpose of this paper is to describe the newly developed blood-flow imaging system "2-D Doppler" and to demonstrate its clinical usefulness in acquired valvular diseases, particularly in the evaluation of valvular regurgitation. The device, in principle, combines a conventional pulsed-Doppler system and a newly developed auto-correlator, in which blood-flow images within a given cross section of a beating heart are noninvasively displayed in real time, simultaneously with conventional two-dimensional echocardiograms. The system can provide three kinds of information, direction, velocity and turbulence of blood flow. The 2-D Doppler examinations were carried out on 72 patients with acquired valvular diseases whose diagnoses were confirmed by angiography and/or surgery. Studies were performed comparing the findings of the 2-D Doppler and those of angiography (for aortic and mitral lesions) or with operative findings (for tricuspid lesions) in the quantitative evaluation of valvular regurgitation. Aortic, mitral and tricuspid valvular regurgitation have been quantitatively demonstrated with 2-D Doppler, and, for each value, the severity of the regurgitation showed a high correlation between the findings of 2-D Doppler and of angiography or surgery. In conclusion, we have found that (1) 2-D Doppler is very useful in detecting and estimating the severity of valvular regurgitation, and that (2) 2-D Doppler may replace conventional angiography in some situations.
长期以来，心脏病学和心血管外科领域一直需要一种使用超声进行实时血流成像的非侵入性方法。最近，我们开发了一种用于临床的二维多普勒超声心动图方法（以下简称为“二维多普勒”），它使我们能够非侵入性地实时获取心内血流图像。本文的主要目的是描述新开发的血流成像系统“二维多普勒”，并展示其在后天性瓣膜疾病中的临床实用性，特别是在评估瓣膜反流方面。该设备原则上结合了传统的脉冲多普勒系统和新开发的自相关器，其中跳动心脏给定横截面内的血流图像可以与传统二维超声心动图同时非侵入性地实时显示。该系统可以提供血流的方向、速度和湍流三种信息。对72例后天性瓣膜疾病患者进行了二维多普勒检查，这些患者的诊断通过血管造影和/或手术得到证实。在瓣膜反流的定量评估中，对二维多普勒检查结果与血管造影（用于主动脉和二尖瓣病变）或手术结果（用于三尖瓣病变）的结果进行了比较研究。二维多普勒已对主动脉、二尖瓣和三尖瓣反流进行了定量显示，并且对于每个值，反流的严重程度在二维多普勒检查结果与血管造影或手术结果之间显示出高度相关性。总之，我们发现：（1）二维多普勒在检测和评估瓣膜反流的严重程度方面非常有用；（2）在某些情况下，二维多普勒可能会取代传统血管造影。
