Isono K
Gan No Rinsho. 1984 Jul;30(9 Suppl):1041-5.
The lymph node metastasis of the esophageal cancer are located in three main regions such as neck (H), thoracic cavity (T) and abdominal cavity (B). We studied on the relation between the extent of lymph node dissection and prognosis, and that between the lymph node metastasis and prognosis in each region (H.T.B). The long-term survival among the cases with adequate dissection, especially with the adequate dissection in the thoracic region, was better than that among the cases without adequate dissection. Furthermore, adequately dissected cases got better survival compared to the cases without adequate dissection with post-operative prophylactic irradiation. However, in the prognosis of the esophageal carcinoma, hematogenous metastasis have to be taken into consideration as well as lymph node metastasis. Therefore, in order to improve the prognosis of esophageal cancer, it is indispensable to treat the multidisciplinary therapy with immunochemotherapy as well as complete lymph node dissection.
食管癌的淋巴结转移主要位于三个主要区域，如颈部（H）、胸腔（T）和腹腔（B）。我们研究了淋巴结清扫范围与预后之间的关系，以及每个区域（H、T、B）的淋巴结转移与预后之间的关系。充分清扫的病例，尤其是胸腔区域充分清扫的病例，其长期生存率优于未充分清扫的病例。此外，与未进行充分清扫且术后接受预防性放疗的病例相比，充分清扫的病例生存率更高。然而，在食管癌的预后中，除了淋巴结转移外，还必须考虑血行转移。因此，为了改善食管癌的预后，采用免疫化疗以及完整的淋巴结清扫进行多学科治疗是必不可少的。
