双亲患糖尿病的后代的血清尿酸浓度

Serum uric acid concentrations in offspring of conjugal diabetic parents.

作者信息

Mohan V, Snehalatha C, Jayashree R, Ramachandran A, Viswanathan M, Kameswaran L, Rocic B, Breyer D, Skrabalo Z

出版信息

Metabolism. 1984 Sep;33(9):869-71. doi: 10.1016/0026-0495(84)90117-3.

Abstract

Serum uric acid concentrations were measured in offspring of conjugal diabetic parents, in diabetic patients, and in matched nondiabetic controls. The mean uric acid level in offspring of conjugal diabetic parents was significantly higher than in the controls and diabetic patients (P less than 0.001 in the nonobese and P less than 0.05 in the obese). Diabetic patients did not show significant differences in the serum uric acid concentration compared to the controls. The elevated level of serum uric acid in offspring of conjugal diabetic parents could possibly be an early biochemical marker of diabetes.

摘要

对双亲均患糖尿病的后代、糖尿病患者以及配对的非糖尿病对照者进行血清尿酸浓度测定。双亲均患糖尿病的后代的平均尿酸水平显著高于对照组和糖尿病患者（非肥胖者P<0.001，肥胖者P<0.05）。与对照组相比，糖尿病患者的血清尿酸浓度无显著差异。双亲均患糖尿病的后代血清尿酸水平升高可能是糖尿病的早期生化标志物。