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密克罗尼西亚城市化人群中高尿酸血症和痛风的高患病率。

High prevalence of hyperuricaemia and gout in an urbanised Micronesian population.

作者信息

Zimmet P Z, Whitehouse S, Jackson L, Thoma K

出版信息

Br Med J. 1978 May 13;1(6122):1237-9. doi: 10.1136/bmj.1.6122.1237.

Abstract

The prevalence of hyperuricaemia and gout was investigated in the Micronesian inhabitants of the highly urbanised central Pacific island of Nauru. Sixty-four per cent of men and 60% of women aged 20 years and over had hyperuricaemia--the highest prevalence rates yet reported for a population. The hyperuricaemia in men was accompanied by a high prevalence of clinical gout (6.9%). While the hyperuricaemia is probably genetic, the high prevalence of gout may be related to the environmental change from the traditional island style of living to one of almost complete Westernisation.

摘要

在高度城市化的中太平洋瑙鲁岛的密克罗尼西亚居民中,对高尿酸血症和痛风的患病率进行了调查。20岁及以上的男性中有64%、女性中有60%患有高尿酸血症——这是迄今为止所报道的人群中最高的患病率。男性的高尿酸血症伴随着临床痛风的高患病率(6.9%)。虽然高尿酸血症可能是遗传性的,但痛风的高患病率可能与从传统岛屿生活方式向几乎完全西化的环境变化有关。

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