Huntley J F, Newlands G, Miller H R
Parasite Immunol. 1984 Jul;6(4):371-90. doi: 10.1111/j.1365-3024.1984.tb00809.x.
Ovine mucosal mast cells and globule leucocytes have been isolated from the abomasum of normal sheep, and from animals challenged with Ostertagia circumcincta. The ultrastructural, morphological and histochemical properties of these cells have been investigated. The granules of ovine mucosal immunoglobulin and a serine esterase. These cells also possess surface immunoglobulin. Cells morphologically intermediate between mucosal mast cells and bulin. Cells morphologically intermediate between mucosal mast cells and globule leucocytes have similar granule and surface properties. These observations, together with quantitative data, indicate that alterations in the granule structure of mucosal mast cells as a consequence of prolonged antigenic challenge give rise to mast cells in the epithelium which, in the past, have been commonly recognized as globule leucocytes.
已从正常绵羊的皱胃以及感染了环形奥斯特他线虫的动物的皱胃中分离出绵羊黏膜肥大细胞和球状白细胞。对这些细胞的超微结构、形态学和组织化学特性进行了研究。绵羊黏膜免疫球蛋白和一种丝氨酸酯酶的颗粒。这些细胞还具有表面免疫球蛋白。在形态上介于黏膜肥大细胞和球状白细胞之间的细胞具有相似的颗粒和表面特性。这些观察结果以及定量数据表明，长期抗原刺激导致黏膜肥大细胞颗粒结构发生改变，从而在上皮中产生了过去通常被认为是球状白细胞的肥大细胞。
