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针对新城疫病毒抗体反应高或低而选育的两个日本鹌鹑品系第7至12代的免疫特性。

Immunological traits in generations 7 to 12 of two lines of Japanese quail selected for high or low antibody response to Newcastle disease virus.

作者信息

Inooka S, Takahashi S, Takahashi H, Mizuma Y

出版信息

Poult Sci. 1984 Jul;63(7):1298-302. doi: 10.3382/ps.0631298.

DOI:10.3382/ps.0631298
PMID:6473242
Abstract

Several immunological traits were compared in lines of Japanese quail selected for high and low secondary immune responses to anti-Newcastle disease virus (NDV). The high line of quail, selected for high ability to produce antibodies, was more responsive in both their primary response to NDV antigen used in the selection as well as to other antigens used in selection process including NDV (Ishi strain), tissue culture-derived Newcastle disease (TCND strain), NDV strain B1, influenza virus, sheep erythrocytes, and Salmonella pullorum than the low line, selected for low ability to produce antibody titers. Mitogenic response to phytohemagglutinin mitogen in the blood lymphocytes from high line quail was more reactive than those from low line quail. Significant line differences were also found in the number of spontaneous rosette cells produced by blood lymphocytes with both fowl and rabbit erythrocytes; the number in the high line exceeded those in the low line.

摘要

在针对抗新城疫病毒(NDV)的高、低二次免疫反应进行选育的日本鹌鹑品系中,对几种免疫特性进行了比较。选育出的高抗体产生能力的鹌鹑品系,在对选育过程中使用的NDV抗原的初次反应以及对选育过程中使用的其他抗原(包括NDV(Ishi株)、组织培养衍生的新城疫(TCND株)、NDV B1株、流感病毒、绵羊红细胞和鸡白痢沙门氏菌)的反应中,都比选育出的低抗体滴度产生能力的低品系鹌鹑更敏感。高品系鹌鹑血液淋巴细胞对植物血凝素丝裂原的促有丝分裂反应比低品系鹌鹑的反应更强。在血液淋巴细胞与鸡和兔红细胞产生的自发玫瑰花结细胞数量上也发现了显著的品系差异;高品系中的数量超过了低品系中的数量。

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引用本文的文献

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The major histocompatibility complex (Mhc) class IIB region has greater genomic structural flexibility and diversity in the quail than the chicken.与鸡相比,鹌鹑的主要组织相容性复合体(Mhc)IIB区域具有更大的基因组结构灵活性和多样性。
BMC Genomics. 2006 Dec 21;7:322. doi: 10.1186/1471-2164-7-322.
2
MHC class IIB gene sequences and expression in quails (Coturnix japonica) selected for high and low antibody responses.针对高抗体反应和低抗体反应选育的鹌鹑(日本鹌鹑)的MHC IIB类基因序列及表达
Immunogenetics. 2004 Jul;56(4):280-91. doi: 10.1007/s00251-004-0690-1. Epub 2004 Jul 16.