Sacco R E, Nestor K E, Saif Y M, Tsai H J, Anthony N B, Patterson R A
Department of Poultry Science, Ohio State University, Wooster 44691.
Poult Sci. 1994 Aug;73(8):1169-74. doi: 10.3382/ps.0731169.
Heritability (h2) of 16-wk BW and primary and secondary antibody responses and genetic and phenotypic correlations among these traits were estimated for 931 male and female turkeys vaccinated with Newcastle disease virus (NDV) and Pasteurella multocida. Turkeys from a line selected for 22 or 23 generations for increased 16-wk BW were vaccinated at 6 and 12 wk of age with blood samples collected 3 wk postvaccination. Antibody titers were determined using an ELISA method and transformed to log(e) for analysis. Heritability estimates for primary and secondary antibody responses to NDV were .380 +/- .070 (SE) and .296 +/- .063, respectively. For primary and secondary antibody responses to P. multocida, h2 estimates were .458 +/- .075 and .333 +/- .066, respectively. Heritability estimate for 16-wk BW was .404 +/- .071. The genetic correlation between primary and secondary antibody responses to NDV was .491 +/- .150. There was no genetic correlation between primary and secondary antibody responses to P. multocida. Although the genetic correlation between primary antibody responses to NDV and P. multocida was .292 +/- .159, the genetic correlation between secondary responses to the two antigens did not differ from zero. There were no genetic correlations between antibody responses and 16-wk BW. Similar results were observed for phenotypic correlations. Based on heritability and genetic correlation estimates, it would be possible to improve antibody responses to either NDV or P. multocida singularly; however, to improve antibody responses to both antigens, selection would have to be applied for each antigen.
对931只接种新城疫病毒（NDV）和多杀性巴氏杆菌的雌雄火鸡，估计了16周龄体重、初次和二次抗体反应的遗传力（h2），以及这些性状之间的遗传和表型相关性。从一个经过22或23代选育以提高16周龄体重的品系中选取的火鸡，在6周龄和12周龄时进行疫苗接种，并在接种后3周采集血样。使用ELISA方法测定抗体滴度，并将其转换为log(e)进行分析。对NDV的初次和二次抗体反应的遗传力估计值分别为0.380±0.070（标准误）和0.296±0.063。对多杀性巴氏杆菌的初次和二次抗体反应，h2估计值分别为0.458±0.075和0.333±0.066。16周龄体重的遗传力估计值为0.404±0.071。对NDV的初次和二次抗体反应之间的遗传相关性为0.491±0.150。对多杀性巴氏杆菌的初次和二次抗体反应之间没有遗传相关性。虽然对NDV和多杀性巴氏杆菌的初次抗体反应之间的遗传相关性为0.292±0.159，但对这两种抗原的二次反应之间的遗传相关性与零无差异。抗体反应与16周龄体重之间没有遗传相关性。表型相关性也观察到类似结果。根据遗传力和遗传相关性估计，有可能单独改善对NDV或多杀性巴氏杆菌的抗体反应；然而，要改善对两种抗原的抗体反应，必须对每种抗原分别进行选择。
