Marcovitz S, Guyda H J, Finlayson M H, Wee R, Hardy J
Surg Neurol. 1984 Oct;22(4):387-96. doi: 10.1016/0090-3019(84)90145-9.
We report two young adult patients with hyperprolactinemia and neuroendocrine deficits due to predominantly intrasellar germinomas. In both cases the diagnosis of germinoma was confirmed histologically after transsphenoidal surgery. This very rare type of tumor may be intrasellar and it may mimic prolactinoma or craniopharyngioma. Dynamic testing of pituitary function and computed tomography scanning are of value in the early detection of this malignant but radiocurable lesion.
我们报告了两名年轻成年患者,他们因主要位于鞍内的生殖细胞瘤而出现高催乳素血症和神经内分泌功能缺陷。在这两个病例中,经蝶窦手术后通过组织学检查确诊为生殖细胞瘤。这种非常罕见的肿瘤类型可能位于鞍内,并且可能类似于催乳素瘤或颅咽管瘤。垂体功能的动态检测和计算机断层扫描对于早期发现这种恶性但可通过放疗治愈的病变具有重要价值。