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一名出现继发性闭经和高催乳素血症的女性患者的原发性鞍内生殖细胞瘤。

Primary intrasellar germinoma in a woman presenting with secondary amenorrhea and hyperprolactinemia.

作者信息

Shen D Y, Guay A T, Silverman M L, Hybels R L, Freidberg S R

出版信息

Neurosurgery. 1984 Sep;15(3):417-20. doi: 10.1227/00006123-198409000-00020.

DOI:10.1227/00006123-198409000-00020
PMID:6483157
Abstract

A 32-year-old woman with secondary amenorrhea was found to have an elevated level of serum prolactin, partial diabetes insipidus, and a subtle visual field defect. A primary intrasellar tumor was noted on the computed tomographic scan. Although the tumor had some characteristics of a prolactinoma, transsphenoidal exploration revealed a primary germinoma. The tissue diagnosis led to appropriate treatment with radiotherapy. The tumor regressed, and the patient had a spontaneous pregnancy. Had dopamine agonists been used initially, amelioration of the hyperprolactinemia and delay in the proper diagnosis and treatment would have occurred.

摘要

一名32岁继发性闭经女性被发现血清催乳素水平升高、部分性尿崩症以及轻微视野缺损。计算机断层扫描显示蝶鞍内有原发性肿瘤。尽管该肿瘤具有一些催乳素瘤的特征,但经蝶窦探查发现是原发性生殖细胞瘤。组织诊断后进行了适当的放射治疗。肿瘤消退,患者自然受孕。如果最初使用多巴胺激动剂,高催乳素血症可能会改善,但会延误正确的诊断和治疗。

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Primary intrasellar germinoma in a woman presenting with secondary amenorrhea and hyperprolactinemia.一名出现继发性闭经和高催乳素血症的女性患者的原发性鞍内生殖细胞瘤。
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