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波氏蝰蛇和宽带蝰蛇毒液的致死效力及免疫电泳图谱

Lethal potencies and immunoelectrophoretic profiles of venoms and Vipera bornmulleri and Vipera latifii.

作者信息

Weinstein S A, Minton S A

出版信息

Toxicon. 1984;22(4):625-9. doi: 10.1016/0041-0101(84)90002-3.

Abstract

Lethality determinations are reported for Vipera bornmulleri and V. latifii. V. latifii venom is significantly more toxic than V. bornmulleri by the i.v. route; by the i.p. and s.c. routes there is little difference between the species. Immunoelectrophoretic profiles indicate close antigenic relationship between venoms of these species and V. palaestinae and Bitis spp.; a more remote relationship with V. russelli and Echis carinatus. Protease activity of V. latifii venom is stronger than that of V. bornmulleri.

摘要

报告了波氏蝰蛇和宽带蝰蛇的致死率测定结果。通过静脉注射途径,宽带蝰蛇毒液的毒性明显高于波氏蝰蛇;通过腹腔注射和皮下注射途径,这两个物种之间差异不大。免疫电泳图谱表明,这些物种的毒液与巴勒斯坦蝰蛇和加蓬咝蝰的毒液之间存在密切的抗原关系;与罗素蝰蛇和锯鳞蝰蛇的关系较远。宽带蝰蛇毒液的蛋白酶活性强于波氏蝰蛇。

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