Rausch R L, Huntley B E
Can J Microbiol. 1978 Feb;24(2):129-35. doi: 10.1139/m78-024.
An investigation of brucellosis caused by Brucella suis, type 4, in reindeer, Rangifer tarandus L., and other ungulates inoculated experimentally with virulent isolates was undertaken to observe the course of infection, follow titres of serum agglutins, and determine the extent to which intraspecific and interspecific transmission might occur among confined animals. Titres rose to maximum levels within 1 to 2 months following inoculation, decreased during the next 4 months, and persisted at low levels thereafter. Titres in uninoculated associates of these animals followed the same pattern, but at lower levels. Abortion occurred in reindeer that received large numbers of organisms; females receiving smaller numbers at an earlier stage of gestation produced normal fawns. Possible explanations for the holarctic distribution of B. suis, type 4, in reindeer are considered.
对4型猪布鲁氏菌引起的驯鹿（Rangifer tarandus L.）布鲁氏菌病以及其他用强毒株分离物进行实验接种的有蹄类动物进行了调查，以观察感染过程、跟踪血清凝集素滴度，并确定圈养动物中种内和种间传播可能发生的程度。接种后1至2个月内，滴度升至最高水平，接下来的4个月内下降，此后维持在低水平。这些动物未接种的同伴的滴度遵循相同模式，但水平较低。接种大量菌的驯鹿发生了流产；在妊娠早期接种少量菌的雌性产下一正常小鹿。文中考虑了4型猪布鲁氏菌在驯鹿中呈环北极分布的可能原因。
