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急性胰腺炎中的脂质改变。

Lipid alterations in acute pancreatitis.

作者信息

Lazaro E J, Bose A K, Spraggins R, Dispenziere B R

出版信息

Can J Surg. 1978 May;21(3):270-1.

PMID:647522
Abstract

The authors studied the lipid profile in acute pancreatitis in humans and also in dogs in which this disease had been induced experimentally. Blood samples were analysed by mass spectroscopy and gas chromatography. During the acute phase of the pancreatitis there was a significant reversal of the ratio of unsaturated fatty acids. There was a marked increase in the concentration of fatty acids in the blood with monounsaturation in both carbon-16 and carbon-18 chains and diunsaturation in the later carbon chains. These changes have not been reported in any disease state.

摘要

作者研究了人类急性胰腺炎患者以及实验性诱发该病的犬类的血脂情况。血样通过质谱分析和气相色谱法进行检测。在胰腺炎急性期,不饱和脂肪酸比例出现显著逆转。血液中碳-16和碳-18链单不饱和以及后碳链双不饱和脂肪酸的浓度显著增加。这些变化在任何疾病状态下均未被报道过。

相似文献

1
Lipid alterations in acute pancreatitis.急性胰腺炎中的脂质改变。
Can J Surg. 1978 May;21(3):270-1.
2
[Content of higher fatty acids and total lipids in blood serum of patients with acute pancreatitis].[急性胰腺炎患者血清中高级脂肪酸和总脂质的含量]
Klin Med (Mosk). 1974 Nov;52(11):70-8.
3
[Fatty acids in the blood in acute viral hepatitis].
Lab Delo. 1981(11):649-52.
4
[Determination of the higher fatty acid content of the blood serum of normal subjects and patients with chronic pancreatitis using gas chromatography].[采用气相色谱法测定正常人和慢性胰腺炎患者血清中的高级脂肪酸含量]
Lab Delo. 1985(9):524-7.
5
[Fatty acid and lipid peroxidation in human atherosclerosis].[人类动脉粥样硬化中的脂肪酸与脂质过氧化]
Sem Hop. 1983 Jun 2;59(22):1657-60.
6
[Plasma lipids in acute experimental pancreatitis].
Z Gesamte Exp Med Einschl Exp Chir. 1968;145(3):302-4.
7
[Blood fatty acid transporters in acute pancreatitis].
Vopr Med Khim. 2001 Nov-Dec;47(6):633-41.
8
Composition of serum fatty acids in healthy children.健康儿童血清脂肪酸的组成
Acta Physiol Pol. 1984 Jan-Feb;35(1):93-100.
9
[Determination of blood serum fatty acids by gas chromatography].
Lab Delo. 1981(10):604-6.
10
Normal canine lipid profiles and effects of experimentally induced pancreatitis and hepatic necrosis on lipids.
Am J Vet Res. 1976 Nov;37(11):1355-7.

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Multimodal Transgastric Local Pancreatic Hypothermia Reduces Severity of Acute Pancreatitis in Rats and Increases Survival.经胃多模态局部胰腺低温治疗可减轻大鼠急性胰腺炎严重程度并提高存活率。
Gastroenterology. 2019 Feb;156(3):735-747.e10. doi: 10.1053/j.gastro.2018.10.034. Epub 2018 Oct 25.
2
Peripancreatic fat necrosis worsens acute pancreatitis independent of pancreatic necrosis via unsaturated fatty acids increased in human pancreatic necrosis collections.胰腺周围脂肪坏死通过人胰腺坏死标本中增加的不饱和脂肪酸,在不依赖胰腺坏死的情况下加重急性胰腺炎。
Gut. 2016 Jan;65(1):100-11. doi: 10.1136/gutjnl-2014-308043. Epub 2014 Dec 10.