Schmidt R E, Heinrichs M, Schilling G, Schüller S, Grube E, Stroehmann I
Z Rheumatol. 1984 May-Jun;43(3):137-41.
17 patients with progressive systemic sclerosis were examined for cardiac involvement using standard ECG, chest X-ray, 24-h Holter ECG, and echocardiography. The control groups consisted of 7 patients with mixed connective tissue disease, 10 patients with systemic lupus erythematosus, and 10 patients with rheumatoid arthritis. The results disclosed a cardiac involvement of 70% using all 4 methods, which is more than is reported in the literature. The data also show that all 4 methods are necessary to diagnose the cardiac involvement. Conduction and rhythm disorders especially are more frequent than in other collagen vascular diseases. The use of calcium channel blockers is discussed as a new therapeutic possibility.
对17例进行性系统性硬化症患者使用标准心电图、胸部X光、24小时动态心电图和超声心动图检查心脏受累情况。对照组包括7例混合性结缔组织病患者、10例系统性红斑狼疮患者和10例类风湿关节炎患者。结果显示,使用所有4种方法检测到心脏受累的比例为70%,高于文献报道。数据还表明,所有4种方法对于诊断心脏受累都是必要的。传导和节律紊乱尤其比其他胶原血管疾病更常见。讨论了使用钙通道阻滞剂作为一种新的治疗可能性。