Hechtman L, Weiss G, Metrakos K
Can Med Assoc J. 1978 Apr 22;118(8):919-21, 923.
In a 10-year follow-up study electroencephalograms (EEGs) of 31 hyperactive and 27 matched control subjects of mean ages 19.17 and 18.59 years respectively showed no significant differences in any of the features assessed. Sequential EEGs, available for only the hyperactive subjects, suggested that a much greater proportion were normal at the 10-year follow-up assessment than at the 5-year follow-up assessment and that the normalization tended to take place mainly in the second 5-year period. This supports the hypothesis that EEG abnormalities of hyperactive persons are those of an immature pattern that tends to normalize with age. Correlation between EEG findings at the 10-year follow-up assessment and global outcome measures was not significant. Initial and 5-year EEGs also failed to predict global outcome at the 10-year follow-up assessment.
在一项为期10年的随访研究中,分别对平均年龄为19.17岁的31名多动患者和平均年龄为18.59岁的27名匹配对照者进行脑电图(EEG)检查,结果显示在评估的任何特征方面均无显著差异。仅对多动患者进行了连续脑电图检查,结果表明,在10年随访评估时,脑电图正常的比例比5年随访评估时高得多,且脑电图正常化趋势主要发生在第二个5年期间。这支持了以下假设,即多动患者的脑电图异常是一种不成熟的模式,且往往会随着年龄增长而正常化。10年随访评估时的脑电图结果与整体结果指标之间的相关性不显著。初始脑电图和5年脑电图也未能预测10年随访评估时的整体结果。