老年患者的钾补充剂与总体钾含量

Potassium supplements and total body potassium in elderly patients.

作者信息

Potter J M, Blake G M, Cox J R

出版信息

Age Ageing. 1984 Jul;13(4):238-42. doi: 10.1093/ageing/13.4.238.

DOI:10.1093/ageing/13.4.238

Abstract

Total body potassium (TBK) and serum potassium measurements have been obtained in nine elderly patients in controlled heart failure on differing diuretic regimens. The patients were randomly maintained on a potassium-sparing diuretic, on frusemide, and on frusemide with potassium supplements (48 mmol/day) for a minimum of one month. TBK levels increased by a mean of 128 mmol on frusemide with potassium supplements compared with no supplements (P less than 0.001), a 7% increase in TBK. Serum potassium levels increased, similarly, from 4.1 mmol/l to 4.8 mmol/l (P less than 0.01). The potassium-sparing diuretic had the same effect as frusemide with supplements in increasing TBK in six patients. However, in three cases there was no increase in TBK compared with frusemide alone. The results demonstrate that potassium supplements are effective in raising TBK levels and serum potassium levels in elderly patients with heart failure.

摘要

已对9例处于控制期心力衰竭的老年患者在不同利尿方案下进行了总体钾（TBK）和血清钾测量。这些患者被随机维持使用保钾利尿剂、速尿以及速尿加钾补充剂（48 mmol/天）至少1个月。与不补充钾相比，服用速尿加钾补充剂时TBK水平平均升高128 mmol（P<0.001），即TBK增加了7%。血清钾水平同样从4.1 mmol/L升高至4.8 mmol/L（P<0.01）。保钾利尿剂在6例患者中增加TBK的效果与速尿加钾补充剂相同。然而，在3例患者中，与单独使用速尿相比，TBK没有增加。结果表明，钾补充剂对于提高老年心力衰竭患者的TBK水平和血清钾水平有效。