钾补充剂、螺内酯或氨氯地平对心力衰竭患者钾状态的影响。
The effects of potassium supplements, spironolactone of amiloride on the potassium status of patients with heart failure.
作者信息
Davidson C, Burkinshaw L, Morgan D B
出版信息
Postgrad Med J. 1978 Jun;54(632):405-9. doi: 10.1136/pgmj.54.632.405.
Abstract
Extra potassium supplements, spironolactone or amiloride were given for 5 months to forty-nine patients with heart failure who were taking furosemide and were in a steady state. Plasma potassium increased with all three treatments but there was no significant increase in total body potassium or red cell potassium. These findings together with other studies suggest that patients with heart failure taking diuretics do not have a significant depletion of body potassium.
摘要
对四十九名正在服用速尿且病情稳定的心力衰竭患者额外补充钾、给予螺内酯或氨氯吡咪五个月。所有三种治疗方法均使血浆钾升高，但总体钾或红细胞钾均无显著增加。这些发现与其他研究共同表明，服用利尿剂的心力衰竭患者体内钾并无显著缺失。
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本文引用的文献
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Lancet. 1961 Apr 1;1(7179):681-7. doi: 10.1016/s0140-6736(61)91719-6.
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Effect of potassium supplements on the exchangeable potassium in chronic heart disease.钾补充剂对慢性心脏病中可交换钾的影响。
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Use of amiloride as a potassium conserving agent in severe cardiac disease.氨氯吡咪作为重症心脏病保钾剂的应用。
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Comparison of the potassium- retaining effects of amiloride and spironolactone in hypertensive patients with thiazide-induced hypokalaemia.氨氯吡咪和螺内酯对噻嗪类药物所致低钾血症高血压患者保钾作用的比较。
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Q J Med. 1976 Jul;45(179):469-78.
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