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1
The effects of potassium supplements, spironolactone of amiloride on the potassium status of patients with heart failure.钾补充剂、螺内酯或氨氯地平对心力衰竭患者钾状态的影响。
Postgrad Med J. 1978 Jun;54(632):405-9. doi: 10.1136/pgmj.54.632.405.
2
[The problem of potassium and diuretics].[钾与利尿剂的问题]
Rev Paul Med. 1972 Sep;80(3):127-32.
3
Effect of potassium-sparing diuretics on the renin-angiotensin-aldosterone system and potassium retention in heart failure.保钾利尿剂对心力衰竭患者肾素-血管紧张素-醛固酮系统及钾潴留的影响
Br Heart J. 1976 Oct;38(10):1025-30. doi: 10.1136/hrt.38.10.1025.
4
[Treatment of cardiac failure with diuretics. A double-blind study comparing a fixed combination of hydrochlorothiazide/amiloride and furosemide plus potassium substitution].
Tidsskr Nor Laegeforen. 1983 May 20;103(14):1165-8.
5
Amiloride, spironolactone, and potassium chloride in thiazide-treated hypertensive patients.氨氯吡咪、螺内酯及氯化钾用于噻嗪类药物治疗的高血压患者
Clin Pharmacol Ther. 1980 Apr;27(4):533-43. doi: 10.1038/clpt.1980.75.
6
Spironolactone and amiloride in hypertensive patients with and without aldosterone excess.螺内酯和氨氯吡咪用于有或无醛固酮增多的高血压患者。
Clin Pharmacol Ther. 1980 Mar;27(3):317-23. doi: 10.1038/clpt.1980.42.
7
[Potassium depletion in cardiology. Action of amiloride, a potassium sparing diuretic].[心脏病学中的钾缺乏。保钾利尿剂阿米洛利的作用]
Acta Cardiol. 1973;28(3):347-57.
8
Comparison of the potassium- retaining effects of amiloride and spironolactone in hypertensive patients with thiazide-induced hypokalaemia.氨氯吡咪和螺内酯对噻嗪类药物所致低钾血症高血压患者保钾作用的比较。
Lancet. 1973 Dec 8;2(7841):1288-91. doi: 10.1016/s0140-6736(73)92869-9.
9
Exchangeable potassium in heart disease: long-term effects of potassium supplements and amiloride.心脏病中的可交换钾：钾补充剂和氨氯吡咪的长期影响。
Am Heart J. 1972 Jul;84(1):53-60. doi: 10.1016/0002-8703(72)90305-5.
10
[Potassium-sparing diuretics (spironolactone, triamterene, amylorid)].保钾利尿剂（螺内酯、氨苯蝶啶、阿米洛利）
Orv Hetil. 1996 Sep 1;137(35):1907-14.

引用本文的文献

1
Errors and misconceptions in drug prescribing.药物处方中的错误与误解。
J R Coll Physicians Lond. 1980 Jan;14(1):58-64.
2
Fixed combination drug therapy.固定复方药物疗法。
Drugs. 1982 Jun;23(6):462-80. doi: 10.2165/00003495-198223060-00003.
3
Total body electrolyte composition in patients with heart failure: a comparison with normal subjects and patients with untreated hypertension.心力衰竭患者的全身电解质组成：与正常受试者及未经治疗的高血压患者的比较。
Br Heart J. 1987 Sep;58(3):230-8. doi: 10.1136/hrt.58.3.230.
4
Diuretics and potassium in the elderly.老年人的利尿剂与钾
J R Coll Physicians Lond. 1987 Apr;21(2):148-52.
5
Potassium replacement: supplements or potassium-sparing diuretics?
Drugs. 1979 Sep;18(3):218-25. doi: 10.2165/00003495-197918030-00004.

本文引用的文献

1
Exchangeable potassium in wasting, amyotrophy, heart-disease, and cirrhosis of the liver.
Lancet. 1961 Apr 1;1(7179):681-7. doi: 10.1016/s0140-6736(61)91719-6.
2
Effect of potassium supplements on the exchangeable potassium in chronic heart disease.钾补充剂对慢性心脏病中可交换钾的影响。
Br Med J. 1970 Jul 18;3(5715):141-2. doi: 10.1136/bmj.3.5715.141.
3
Use of amiloride as a potassium conserving agent in severe cardiac disease.氨氯吡咪作为重症心脏病保钾剂的应用。
Br Heart J. 1973 Apr;35(4):456-61. doi: 10.1136/hrt.35.4.456.
4
Comparison of the potassium- retaining effects of amiloride and spironolactone in hypertensive patients with thiazide-induced hypokalaemia.氨氯吡咪和螺内酯对噻嗪类药物所致低钾血症高血压患者保钾作用的比较。
Lancet. 1973 Dec 8;2(7841):1288-91. doi: 10.1016/s0140-6736(73)92869-9.
5
Fate of potassium supplements in six outpatients receiving long-term diuretics for oedematous disease.
Lancet. 1972 Oct 7;2(7780):721-4. doi: 10.1016/s0140-6736(72)92018-1.
6
Effect of potassium-sparing diuretics on the renin-angiotensin-aldosterone system and potassium retention in heart failure.保钾利尿剂对心力衰竭患者肾素-血管紧张素-醛固酮系统及钾潴留的影响
Br Heart J. 1976 Oct;38(10):1025-30. doi: 10.1136/hrt.38.10.1025.
7
Potassium supplements in patients receiving long-term diuretics for oedema.接受长期利尿剂治疗水肿患者的钾补充剂。
Q J Med. 1976 Jul;45(179):469-78.
8
Potassium depletion in heart failure and its relation to long-term treatment with diuretics: a review of the literature.心力衰竭中的钾缺乏及其与利尿剂长期治疗的关系：文献综述
Postgrad Med J. 1978 Feb;54(628):72-9. doi: 10.1136/pgmj.54.628.72.
9
Effect of long-term diuretic treatment on body-potassium in heart-disease.长期利尿治疗对心脏病患者体内钾含量的影响。
Lancet. 1976 Nov 13;2(7994):1044-7. doi: 10.1016/s0140-6736(76)90965-x.

钾补充剂、螺内酯或氨氯地平对心力衰竭患者钾状态的影响。

The effects of potassium supplements, spironolactone of amiloride on the potassium status of patients with heart failure.

作者信息

Davidson C, Burkinshaw L, Morgan D B

出版信息

Postgrad Med J. 1978 Jun;54(632):405-9. doi: 10.1136/pgmj.54.632.405.

DOI:10.1136/pgmj.54.632.405
PMID:683909
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2425175/
Abstract

Extra potassium supplements, spironolactone or amiloride were given for 5 months to forty-nine patients with heart failure who were taking furosemide and were in a steady state. Plasma potassium increased with all three treatments but there was no significant increase in total body potassium or red cell potassium. These findings together with other studies suggest that patients with heart failure taking diuretics do not have a significant depletion of body potassium.

摘要

对四十九名正在服用速尿且病情稳定的心力衰竭患者额外补充钾、给予螺内酯或氨氯吡咪五个月。所有三种治疗方法均使血浆钾升高，但总体钾或红细胞钾均无显著增加。这些发现与其他研究共同表明，服用利尿剂的心力衰竭患者体内钾并无显著缺失。