Ibrahim I K, Ritch A E, MacLennan W J, May T
Age Ageing. 1978 Aug;7(3):165-70. doi: 10.1093/ageing/7.3.165.
Plasma and total-body potassium (TBK) were measured in 19 elderly patients receiving diuretics and potassium supplements for cardiac failure and in 13 elderly controls. The mean value for the ratio of TBK to fat-free mass (TBK:FFM) was significantly reduced in the patient group. TBK:FFM showed a negative correlation with age but no correlation with plasma potassium or dose of supplements. When controls and patients were matched for sex and age decade, the mean TBK:FFM was decreased significantly in the diuretic group, giving a mean potassium deficit of 13.3%. These results suggest that ageing influences potassium status, and that diuretics and cardiac failure have a greater effect on TBK in old age than in youth or middle age.
对19名因心力衰竭接受利尿剂和钾补充剂治疗的老年患者以及13名老年对照组进行了血浆和全身钾(TBK)测量。患者组中TBK与去脂体重(TBK:FFM)的比值平均值显著降低。TBK:FFM与年龄呈负相关,但与血浆钾或补充剂剂量无关。当对照组和患者按性别和年龄十年进行匹配时,利尿剂组的平均TBK:FFM显著降低,平均钾缺乏率为13.3%。这些结果表明,衰老会影响钾状态,并且利尿剂和心力衰竭对老年人TBK的影响比对年轻人或中年人更大。