Kawamura J, Hiura M, Kuo Y J, Hatayama T, Tobisu K, Kita Y, Terai A, Ogawa O, Okamura Y, Ohishi K
Hinyokika Kiyo. 1984 May;30(5):589-98.
Ultrasound-guided renal cyst puncture was performed on 22 cysts which were then 95% ethanol instilled to prevent recurrence of cystic fluid. Cystic lesions disappeared on the ultrasonogram in the follow-up period of 3 to 28 months. On CT, cystic lesions became smaller size but did not disappear. Average CT numbers of the cyst were 8.75 +/- 3.83 before and 12.96 +/- 3.27 after ethanol instillation. The cystic wall became thicker. Caliceal distortion and/or pelvis compression by cystic lesions improved on IVP 2 to 3 days after ethanol instillation. The renal image on Tc-99m-DMSA scintigram showed morphological improvement and DMSA renal uptake rate increased slightly but significantly 2 to 4 weeks after ethanol instillation. There were no major complications with this procedure except for one case in which the tip of the catheter became stuck in the cyst and broke off when the catheter was removed. A slight local irritable pain was noticed in all cases. Half of the patients had hot flushes and/or somewhat drunken sense but these symptoms were only temporary. Antabuse phenomenon appeared in one case with concomitant use of a cephem antibiotics after ethanol instillation. This method of therapy is a safe non-surgical approach to treat renal cysts. 95% ethanol instillation in the cyst seems to prevent recurrence of cystic fluid.
对22个肾囊肿进行了超声引导下肾囊肿穿刺,然后向囊肿内注入95%乙醇以防止囊液复发。在3至28个月的随访期内,超声检查显示囊性病变消失。在CT上,囊性病变变小但未消失。乙醇注入前囊肿的平均CT值为8.75±3.83,注入后为12.96±3.27。囊壁增厚。乙醇注入后2至3天,静脉肾盂造影显示囊性病变对肾盏的压迫和/或对肾盂的压迫有所改善。乙醇注入后2至4周,99mTc-DMSA肾闪烁显像显示肾脏形态改善,DMSA肾摄取率略有但显著增加。除1例导管尖端卡在囊肿内,拔除导管时折断外,该操作无重大并发症。所有病例均出现轻微局部刺激性疼痛。一半患者出现潮热和/或有点醉酒感,但这些症状只是暂时的。1例在乙醇注入后同时使用头孢菌素抗生素出现戒酒硫样反应。这种治疗方法是一种治疗肾囊肿的安全非手术方法。向囊肿内注入95%乙醇似乎可防止囊液复发。