Fuchs J, Weinberger I, Rotenberg Z, Erdberg A, Davidson E, Joshua H, Agmon J
Am Heart J. 1984 Sep;108(3 Pt 1):435-9. doi: 10.1016/0002-8703(84)90405-8.
Plasma viscosity was measured by the capillary method in 108 patients with ischemic heart disease. The highest value of plasma viscosity was found in 11 patients with severe unstable angina (1.66 +/- 0.068), while in 18 patients with less severe unstable angina plasma viscosity was lower (1.61 +/- 0.056; p less than 0.025). In 43 patients with acute myocardial infarction plasma viscosity was 1.53 +/- 0.10, significantly lower than in the two groups with unstable angina (p less than 0.005). In 36 patients with stable angina plasma viscosity was 1.42 +/- 0.089, similar to that found in 100 normal subjects. Plasma viscosity did not increase in 30 ischemic heart disease patients during exercise-induced myocardial ischemia. It is suggested that the elevated plasma viscosity in unstable angina demonstrated in this study compromises the oxygen delivery to the myocardium and coronary blood flow and therefore may possibly be a factor in the pathophysiology of this syndrome.
采用毛细管法对108例缺血性心脏病患者进行血浆黏度测定。11例严重不稳定型心绞痛患者的血浆黏度最高值为（1.66±0.068），而18例轻度不稳定型心绞痛患者的血浆黏度较低（1.61±0.056；p＜0.025）。43例急性心肌梗死患者的血浆黏度为1.53±0.10，显著低于不稳定型心绞痛的两组患者（p＜0.005）。36例稳定型心绞痛患者的血浆黏度为1.42±0.089，与100例正常受试者的结果相似。30例缺血性心脏病患者在运动诱发心肌缺血期间血浆黏度未升高。本研究表明，不稳定型心绞痛患者血浆黏度升高会损害心肌的氧输送和冠状动脉血流，因此可能是该综合征病理生理学中的一个因素。
