Margileth A M, Chandra R, Altman R P
Am J Dis Child. 1984 Oct;138(10):917-22. doi: 10.1001/archpedi.1984.02140480019007.
This report provides clinical information, diagnostic criteria, management, and outcome of 153 cases of mycobacterial lymphadenitis; 22 patients (14%) had Mycobacterium tuberculosis (TB) and 131 patients (86%) had nontuberculous mycobacterial (NTM) disease. Correct diagnosis of TB v NTM disease is essential, since antituberculous chemotherapy was effective for TB adenitis, while excisional biopsy was the treatment of choice for NTM adenopathy. Dual (PPD-NTM, PPD-T) Mantoux tests discriminated between TB and NTM adenitis in 151 (99%) of 153 patients, while dual (PPD-Battey [B], PPD-T) tests differentiated between NTM and TB adenitis in 135 (88%) of 153 cases. A PPD-T reaction of 1 to 14 mm suggested either an NTM or TB infection, whereas a PPD-T of 15 mm or greater was strongly associated with TB disease. We recommend the use of PPD-B and PPD-T antigens as reliable diagnostic discriminators between TB and NTM adenitis.
本报告提供了153例分枝杆菌性淋巴结炎的临床信息、诊断标准、治疗及预后情况；22例患者（14%）患有结核分枝杆菌（TB）感染，131例患者（86%）患有非结核分枝杆菌（NTM）疾病。准确诊断TB与NTM疾病至关重要，因为抗结核化疗对TB腺炎有效，而手术切除活检是NTM腺病的首选治疗方法。双（PPD-NTM、PPD-T）结核菌素试验在153例患者中的151例（99%）中区分了TB和NTM腺炎，而双（PPD-巴特尔[B]、PPD-T）试验在153例病例中的135例（88%）中区分了NTM和TB腺炎。PPD-T反应为1至14毫米提示NTM或TB感染，而PPD-T为15毫米或更大则与TB疾病密切相关。我们建议使用PPD-B和PPD-T抗原作为TB和NTM腺炎之间可靠的诊断鉴别指标。
