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马萨诸塞州的癌症与职业:一项死亡证明研究。

Cancer and occupation in Massachusetts: a death certificate study.

作者信息

Dubrow R, Wegman D H

出版信息

Am J Ind Med. 1984;6(3):207-30. doi: 10.1002/ajim.4700060305.

Abstract

This study examines cancer mortality patterns by occupation for white males in Massachusetts using 1971-1973 death records. Its purpose is to identify occupation-cancer associations that, when interpreted in conjunction with results from other studies and hypotheses about potential occupational carcinogens, can serve as leads for more definitive etiological investigations. Sixty-two malignancy categories (including grouped categories) were investigated for each of 397 occupational categories (including grouped categories) using an age-standardized mortality odds ratio approach. An important finding was the association between lung cancer and a large number of occupations for which there is support from other epidemiologic studies and/or for which there are reasonable hypotheses as to possible carcinogenic exposures. These occupations include truck drivers, painters, machinists, automobile mechanics, plumbers, cooks, fishermen, heated metal workers, sheet metal workers, and brickmasons/stonemasons/tile setters.

摘要

本研究利用1971 - 1973年的死亡记录,调查了马萨诸塞州白人男性按职业划分的癌症死亡模式。其目的是确定职业与癌症之间的关联,当结合其他研究结果和关于潜在职业致癌物的假设进行解释时,这些关联可为更明确的病因学调查提供线索。使用年龄标准化死亡率比值比方法,对397个职业类别(包括分组类别)中的每一个类别,调查了62种恶性肿瘤类别(包括分组类别)。一个重要发现是肺癌与大量职业之间的关联,其他流行病学研究为这些职业提供了支持,和/或对于可能的致癌暴露存在合理的假设。这些职业包括卡车司机、油漆工、机械师、汽车修理工、水管工、厨师、渔民、热金属工人、钣金工人以及砖瓦匠/石匠/瓷砖安装工。

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