Ruas P M, Freire-Maia N
Am J Med Genet. 1984 Jul;18(3):381-6. doi: 10.1002/ajmg.1320180304.
Data from two surveys performed in Brazil and involving 5,719 persons have been subdivided into three subsamples (one with cousin and sib controls). The totals led to estimates of B (abnormal equivalents per gamete) around 0.5, of A (the damage in a noninbred population) around 0.01-0.02, and of B/A from 14 to 77. No statistically significant difference was found between whites and nonwhites (mulattoes and Negroes). Inbreeding seems to disclose a predominantly mutational load.
来自巴西进行的两项调查、涉及5719人的数据已被细分为三个子样本（一个有堂兄弟姐妹和同胞作为对照）。总体数据得出B（每个配子的异常当量）约为0.5，A（非近亲繁殖群体中的损伤）约为0.01 - 0.02，B/A为14至77。白人与非白人（混血儿和黑人）之间未发现统计学上的显著差异。近亲繁殖似乎揭示了一种主要的突变负荷。
