Hoffstein V, Zamel N
Am Rev Respir Dis. 1984 Sep;130(3):472-5. doi: 10.1164/arrd.1984.130.3.472.
We examined the usefulness of the acoustic reflection technique for measurement of airway area in 6 patients with tracheal stenosis. In each patient, we obtained airway area by acoustic reflections in the upright position, maximal expiratory and inspiratory flow-volume curve, and radiographs of the trachea. We identified acoustic and radiographic stenotic segments and compared their length, their distances from the glottis, and their cross-sectional areas. We found that (1) in all subjects except one, flow-volume curves did not suggest upper airway obstruction, (2) tracheal stenosis was confirmed by acoustic and radiographic measurements in all subjects, and (3) area of the stenotic segment showed less variation with lung volume than that of the nonstenotic segment. Length of the stenotic segment (mean +/- SE) was found to be 4.9 +/- 0.2 cm (acoustic versus 4.8 +/- 0.3 cm (radiographic); distance between the midglottis and maximal stenosis was 5.7 +/- 0.4 cm (acoustic) and 5.6 +/- 0.6 cm (radiographic); minimal acoustic cross-sectional area was 1.7 +/- 0.1 cm2 versus a radiographic circular cross-sectional area of 1.2 +/- 0.1 cm2. During slow expiration from total lung capacity to residual volume, average cross-sectional area of the stenotic segment decreased by 19.5 +/- 3.0% (mean +/- SE), whereas that of the distal nonstenotic segment decreased by 48.5 +/- 2.2% and that of the proximal nonstenotic segment by 43.6 +/- 5%. We conclude that the acoustic technique, which is rapid and noninvasive, is useful in confirming tracheal stenosis in patients with normal flow-volume curves, and in assessing elastic properties of the trachea.
我们研究了声学反射技术在测量6例气管狭窄患者气道面积方面的实用性。对每例患者,我们通过直立位的声学反射、最大呼气和吸气流量-容积曲线以及气管X线片来获取气道面积。我们确定了声学和X线片上的狭窄节段,并比较了它们的长度、距声门的距离以及横截面积。我们发现:(1)除1例患者外,所有受试者的流量-容积曲线均未提示上气道梗阻;(2)所有受试者均通过声学和X线片测量确诊为气管狭窄;(3)狭窄节段的面积随肺容积的变化小于非狭窄节段。狭窄节段的长度(均值±标准误)经声学测量为4.9±0.2 cm,经X线片测量为4.8±0.3 cm;声门中点与最大狭窄处之间的距离经声学测量为5.7±0.4 cm,经X线片测量为5.6±0.6 cm;最小声学横截面积为1.7±0.1 cm²,而X线片圆形横截面积为1.2±0.1 cm²。从肺总量缓慢呼气至残气量时,狭窄节段的平均横截面积下降了19.5±3.0%(均值±标准误),而远端非狭窄节段下降了48.5±2.2%,近端非狭窄节段下降了43.6±5%。我们得出结论,声学技术快速且无创,对于确诊流量-容积曲线正常的患者的气管狭窄以及评估气管的弹性特性是有用的。