Tiep B L, Nicotra B, Carter R, Belman M J, Mittman C
Am Rev Respir Dis. 1984 Sep;130(3):500-2. doi: 10.1164/arrd.1984.130.3.500.
Oxygen therapy is one of the most frequently ordered therapies for patients with chronic obstructive pulmonary disease (COPD). In a large percentage of these cases, oxygen therapy is supplied via nasal cannula. With the rising cost of medical care and the search for more effective means of oxygen delivery, a new oxygen-conserving nasal cannula (CNC) that incorporates a closely coupled 20-ml reservoir was developed. Oxygen is stored in the reservoir during exhalation so that 20 ml of approximately 85% oxygen is the first gas inhaled. To test the hypothesis that the CNC is more efficient than the standard nasal cannula (SNC), 20 patients with COPD were evaluated. All patients were chronically hypoxemic at rest. Results indicate that when the CNC was compared with the SNC, arterial oxygen saturation levels were significantly different (p less than 0.001) at flow rates of 0.5, 1.0, and 2.0 L/min. Oxygen saturation were 2.9% higher at 0.5 L/min, 2.9% higher at 1 L/min, and 2.6% higher at 2 L/min for the CNC than for the SNC. In summary, the CNC offers a more efficient oxygen delivery system for those patients requiring supplemental oxygen administration by nasal cannula.
氧疗是慢性阻塞性肺疾病（COPD）患者最常使用的治疗方法之一。在这些病例中，很大一部分患者通过鼻导管接受氧疗。随着医疗费用的不断上涨以及对更有效氧输送方式的探索，一种新型的带有紧密耦合的20毫升储氧器的节氧鼻导管（CNC）被研发出来。呼气时氧气被储存在储氧器中，这样吸入的第一口气体约为20毫升含氧量约85%的氧气。为了验证节氧鼻导管比标准鼻导管（SNC）更高效这一假设，对20名慢性阻塞性肺疾病患者进行了评估。所有患者在静息状态下均长期存在低氧血症。结果表明，将节氧鼻导管与标准鼻导管进行比较时，在流速为0.5、1.0和2.0升/分钟时，动脉血氧饱和度水平存在显著差异（p小于0.001）。节氧鼻导管在0.5升/分钟时的血氧饱和度比标准鼻导管高2.9%，在1升/分钟时高2.9%，在2升/分钟时高2.6%。总之，对于那些需要通过鼻导管进行补充输氧的患者，节氧鼻导管提供了一种更高效的氧输送系统。
